The active ingredients are sulpiride and mebeverine hydrochloride.Sulpiride is a selective central dopamine D2 receptor blocker that exerts a mood elevating effect (due to its neuroleptic effect) and anti-emetic action.Mebeverine hydrochloride is a smooth muscle relaxant that works by relaxing the muscles of the gastrointestinal tract.Additional information:Colona Tablets may cause side effects such as drowsiness, dizziness, and headache.It is important to talk to your doctor about any side effects that you experience while taking this medication.Please note that this is not a complete list of information about Colona 30 Film Coated Tablets.It is always best to talk to your doctor about any questions that you have about this medication.