Antibiotic, belongs to Cephalosporin group (Third Generation) used in the treatment of acute bacterial rhinosinusitis, gonococcal infection, streptococcal pharyngitis, urinary tract infection and Typhoid fever.
Indication & Usage
-Acute bacterial rhinosinusitis: Oral: 400 mg once daily with clindamycin for 5 to 7 days; some experts use as monotherapy when the risk of drug-resistant streptococcus pneumoniae is low (eg, <65 years of age, low endemic resistance, few comorbidities, no recent hospitalization or antibiotic use). -Streptococcal pharyngitis: Oral: 400 mg once daily for 10 days. -Gonococcal infection: Oral: 800 mg as a single dose; give in combination with treatment for chlamydia if it has not been excluded. -Urinary tract infection: Acute uncomplicated cystitis: Oral: 400 mg once daily for 7 days. While in case of complicated urinary tract infection (including pyelonephritis) : Oral: 400 mg once daily for 10 to 14 days. -Typhoid fever: Oral: 100 to 200 mg twice daily for 7 to 14 days. -Pediatric dosing: -General dosing; susceptible infection (mild to moderate): Infants, children, and adolescents: Oral: 8 mg/kg/day once daily or in divided doses every 12 hours; maximum daily dose: 400 mg/day. -Otitis media, acute: Oral suspension or chewable tablets: Infants, Children, and Adolescents: Oral: 8 mg/kg/day once daily or in divided doses every 12 hours; maximum daily dose: 400 mg/day. -Streptococcus pyogenes pharyngitis or tonsillitis: Infants, children, and adolescents: Oral: 8 mg/kg/day once daily or in divided doses every 12 hours for 10 days; maximum daily dose: 400 mg/day. -Acute bacterial rhinosinusitis: Infants, children, and adolescents: Oral: 8 mg/kg/day once daily or in divided doses every 12 hours with concomitant clindamycin for 10 to 14 days; maximum daily dose: 400 mg/day. -Acute urinary tract infection: Infants ≥2 months, children, and adolescents: Limited data available in infants <6 months: Oral: 8 mg/kg/day once daily or in divided doses every 12 hours for 7 to 14 days.