Downoprazol Oral Suspension Powder with Omeprazole & Sodium Bicarbonate

Warning:The dose below is calculated based on the omeprazole component only.(Sodium bicarbonate component of this medication can be taken in a dose of 325 mg to 2 g once to four times/day). -Gastroesophageal reflux disease:Initial therapy:Mild/intermittent disease (<2 episodes/week) and no evidence of erosive esophagitis:Oral: 10 mg once daily; can increase to 20 mg once daily after 4 to 8 weeks if necessary. Discontinue once asymptomatic for 8 weeks.Severe and/or frequent symptoms (≥2 episodes/week) and/or erosive esophagitis:Oral: 20 to 40 mg once daily; once symptoms are controlled, continue for at least 8 weeks. -Heartburn, frequent symptoms (≥2 episodes/week):Oral: 20 mg once daily for 14 days (maximum: 20 mg/day); may repeat a 14-day course every 4 months if needed. -Treatment and secondary prevention of peptic ulcer disease:Uncomplicated ulcer:Oral: 20 to 40 mg once daily. Duration depends on the size, location, and cause of the ulcer and ranges from 4 to 8 weeks. In patients with refractory or recurrent disease, may increase the dose to 20 to 40 mg twice daily. -Stress ulcer prophylaxis in select critically ill patients: Oral or via NG tube (oral suspension or capsule [off label]): 40 mg once daily or 40 mg initially, then another 40 mg dose given 6 to 8 hours later, followed by 40 mg once daily. -Pediatric dosing: Erosive esophagitis: Treatment: Duration of therapy is dependent on age: Infant duration is up to 6 weeks and children and adolescent duration is 4 to 8 weeks. For recurrence of erosive esophagitis or gastroesophageal reflux disease (GERD) symptoms, an additional 4- to 8-week course may be considered.Infants, Children, and Adolescents: Oral: 3 to <5 kg: 2.5 mg once daily, 5 kg to <10 kg: 5 mg once daily, 10 kg to <20 kg: 10 mg once daily, ≥20 kg: 20 mg once daily. Maintenance of healing: Children and Adolescents: Oral:5 kg to <10 kg: 5 mg once daily, 10 kg to <20 kg: 10 mg once daily, ≥20 kg: 20 mg once daily.