14 tablets
Medical Description
Combination therapy consisting of two antilipidemic agents; ezetimibe and the HMG-CoA Reductase Inhibitor; simvastatin used in the treatment of hypercholesterolemia.
Indication & Usage
-Homozygous familial hypercholesterolemia: Oral: Ezetimibe 10 mg and simvastatin 40 mg once daily in the evening. -Primary hyperlipidemia: Oral: Initial: Ezetimibe 10 mg and simvastatin 10 to 20 mg once daily in the evening. -Pediatric dosing: Heterozygous familial hypercholesterolemia: Limited data available: Children ≥10 years and adolescents: Oral: Initial: Ezetimibe 10 mg and simvastatin 10 to 20 mg once daily in the evening.
Active Ingredients
Simvastatin
Ezetimibe
Dosage & Administration
-Administered without regard to meals. -Administer in the evening for maximal efficacy. -Ezetimibe/simvastatin should be taken ≥2 hours before or ≥4 hours after administration of a bile acid sequestrant.